What would help your body prevent or get rid of Acne Scars?
The acne scar treatment and prevention products you find nowadays are aimed at replenishing skin matrix by stimulating the synthesis of collagen or elastin (e.g. those containing ingredients such as ascorbic acid, copper peptides, palmitoyl pentapeptide or oligopeptides).
Unfortunately, this approach fails or falls short in most people affected by atrophic skin, whereby skin is too thin and not strong enough to support stretching beyond what it has been used too, presumably due to the particular chemistry of skin affected by such condition and an inability to respond to matrix synthesis boosters.
The failure is because something crucial missing in those products: that which would help your own body get rid of scar tissues and would help to prevent Acne Scars by strengthening your skin and supporting it to become more resilient.
What needs to be there to treat Acne Scars?
Two things acting in concert. First, your body needs to be able to differentiate or identify scar tissue from the surrounding functional tissues in the skin matrix. Second, it must be able to degrade the proteins that those scar tissues are made off and separate their component amino-acids and use them to create new skin matrix elements.
This can only be achieved by the concerted action of two types of ingredients.
One are messenger molecules that are able to bridge communication between cells and allow them to differentiate scar tissues from functional healthy skin tissues.
The other crucial ingredient are enzymes that both dissolve or “digest” non functional cells, worn out or damaged skin cells AND trigger proliferation of new collagen and elastin fibers from within the skin matrix.
Acne Scars are visible linear scars. These form in areas of dermal damage produced when skin is not capable of withstanding over-stretching and the elastin and collagen fibers reach tensile capacity. They weaken and ultimately fail resulting in tears in the dermal skin layer.
They show up on a thinned skin surface as visibly curled stripes and are actually bands of elastin broken beneath the skin. Essentially, Acne Scars are scars that have formed from the inside out, rather than scarring from external wounds.
Scanning electron microscopy shows extensive tangles of fine, curled elastic fibers with a random arrangement. This arrangement is in contrast to normal skin, which has thick, elastic, fibers with a regular distribution.
Elastin is a protein that coils and recoils like a spring within the elastic fibers of connective tissue and accounts for the elasticity of structures such as the skin, blood vessels, heart, lungs, intestines, tendons, and ligaments. Elastin functions in connective tissue together with collagen. Whereas elastin provides elasticity, collagen provides rigidity to connective tissue.
Acne Scars occur frequently during pregnancy, growth spurts, bodybuilding while on steroids, or when other hormonal imbalances may be at work. It may surprise you to know that in the United States it is estimated that 90% of pregnant women, 70% of adolescent females, and 40% of adolescent males have Acne Scars.
There does not seem to be an ethnic tendency toward Acne Scars, as people of all skin colors can be affected. People who have fair to light skin typically have pink-tinged Acne Scars, while the same marks on darker skin tones tend to take on a deeper pigmentation than the skin surrounding them. Discoloration from Acne Scars does fade over time, but regrettably, their striated appearance rarely returns to its original smooth appearance.
It is speculated that the way each person's skin heals is a good indicator of the depth and severity of Acne Scars they may eventually see. A person whose skin heals well with minimal scarring can expect less obvious Acne Scars, while skin that heals poorly (or slowly) or tends to develop raised or thickened scars can generally expect Acne Scars that are more pronounced.
Acne Scars are caused by TEARS in a thinned or technically atrophic skin, with fine dermal collagen bundles arranged in straight lines parallel to the surface, created by your own body to heal those tears. Let me repeat that: Acne Scars are scar tissue created by your own body to heal damage caused by overly stretching skin that is too thin. Your body creates them to heal itself as quickly as it can possible do with its own resources. Once those scars are formed and prominent because of their depth, length, discoloration, and texture it is very difficult to get rid of them.
Atrophic definition: a wasting or decrease in the size of an organ or tissue, as from death and re-absorption of cells, diminished cellular proliferation, pressure, ischemia, malnutrition, decreased function, or hormonal changes, also called atrophia.
Many different treatment creams have tried to prevent or improve the appearance of Acne Scars. Most of them, as well as most of the abrading methods used to treat existing marks, do not have the slightest possibility of being effective.
Most acne scar Products Only Address The Symptoms:
• Skin Dryness: Acne Scars are not caused because your skin is dry.
Rather Acne Scars develop far below the skin's surface due to extreme strain, stress, and trauma that eventually breaks down the skin's support structure. No moisturizer in the world can prevent that kind of injury and damage to the skin from taking place.
• Treatment of superficial scar tissues: with harsh acids, dermabrasion, laser, etc., attempting to breakdown scarring but act only on the surface and not deep enough into the dermis where scar tissues have formed to reconnect teared skin fibres.
They can help with newly formed Acne Scars a little, although they may all have adverse side effects such as erythema (redness) and scaling.
One of the products widely used is tretinoin, but not for women who are pregnant or about to get pregnant for it may cause damage to the growing child in mom’s belly, and is also contraindicated for mothers that breastfeed their baby, so treatment can only begin when it may be too late for the body to act upon the scar tissues with its help.
• Products containing collagen and elastin. Consumers are catching on to the idea that if an active ingredient can't penetrate into the skin, what good is it? For years, companies touted collagen-rich products, saying that applying collagen would somehow stimulate more production of your own collagen, deep in the dermis. But collagen is such a big molecule it can't penetrate the skin's outer layer. And now that that's been shown through studies, we're seeing a lot less hype about collagen.
• Boosting collagen synthesis, with man made synthetic chemicals, which are not enough to prevent Acne Scars or treat existing Acne Scars. It is also necessary to degrade the existing damaged and worn out cells. And not only to get rid of them and their ugly marks on the body, but because the release of their components makes available the amino-acids or building blocks your system needs to create new collagen, elastin, and skin matrix cells to strengthen the skin.
Natural Breakthrough Product works because it addresses the root cause of Acne Scars and not just the symptoms:
• Restores skin's strength: skin affected by Acne Scars is characterized by weakness, thinning, roughness, sagging, stiffness, and decrease in the size of tissues, diminished cellular proliferation and decreased function, also called atrophia.
• Dissolves Deep Scar Tissues with gentle enzymes that "digest" the non functional tissues and release amino-acids that help rebuild damaged tissues quickly and without peeling and no dryness. On the contrary, while moisturizing the skin deeply and triggering healthy skin regeneration.
• Provides the skin the missing messenger molecules that are able to bridge communication between cells and allows them to differentiate scar tissues from functional healthy tissues.
• Collagen and elastin synthesis boosters: those are also messenger molecules that trigger fibroblast proliferation, the cells responsible for the production of all structural elements in skin.
Combined methods that include some form of abrading —to physically break down some of the more superficial scarring—, plus collagen synthesis boosters, cell communicating ingredients and enzymes, ACTING IN CONCERT can ‘dissolve’ damaged cells and scar proteins, trigger collagen, and new elastin formation, and strengthen the skin's structure by replenishing the skin's glycosaminoglycans, the water holding molecules in the dermis responsible for providing binding, hydrating and swelling pressure to tissues enabling them to withstand compression and stretching forces and thus prevent tearing and scarring of the deep layers of the skin.
Why abrading methods purported to correct and even eliminate Acne Scars fail.
Dermabrasion is an abrasive procedure used to get rid of the superficial damaged skin layer with a diamond fraise. This method is performed superficially. If carried out more deeply, it can generate a condition called dyschromia (patchy pigment), some mild scarring or even rupture of the skin at the depth of Acne Scars, making things worse.
Microdermabrasion is a technique that evolved from dermabrasion and consists in blasting micro-crystals to abrade or sand the superficial layer of skin. It is good for rough superficial uneven skin texture, as it smoothes it out, but tends to give uneven results. It may be unpleasant and if done too deep scarring is likely to occur.
Lasers get rid of the superficial layer of skin by burning it but are not that effective with old Acne Scars, quite contrary they only work for new developed Acne Scars. Still, even though the stripes might be pink or red, studies reporting the use of Intense Pulsed Light (IPL) and Pulsed Dye Laser (PDL) treatments emitting 585 nanometers (nm) of light conclude that after five sessions the improvement shown in the length, depth, and coloration of Acne Scars is at most, moderate.
And although this type of laser carries a low risk of side effects and complications when operated at appropriate treatment parameters and time intervals, they are not recommended for use on darker skin tones (including African-American) because of the risk of hyper pigmentation.
Cost for a series of laser treatments can run upwards of $2,500 depending on how your skin responds and what the average fees are in your area.
Superficial peels are generally performed with glycolic acid. The practice of glycolic acid treatment over Acne Scars is disappointing. This is not unexpected as alpha-hydroxy acids act only superficially, mainly by lessening the bonds of the stratum corneum cells.
Medium depth peels with standard Trichloracetic acid (TCA) at 35% to 50% (mass per volume) applied by a dermatologist or cosmetic surgeon, skilled in the use of this type of peel, obtain very irregular results. The side effects have been scarring and dark spots. A benefit of TCA peels (and the reason it can help improve the appearance of Acne Scars) is their skin-tightening effect.
Deep peels with phenol are extremely dangerous for extra facial dermal tissue, because of their possibility for life threatening complications; local scarring and enduring hypochromia (a decrease in the amount of hemoglobin found in red blood cells) are some of the outcomes.
Topical creams for treatment and/or prevention
They range from those with ascorbic acid (10%) or tretinoin (0.05% tretinoin emollient cream - trans retinoic acid cream) to ointments with glycolic acid; biological moisturizing oils, like Emu oil, Rose Hip Oil; Olive Oil and Squalene and other of its derivatives, Cocoa Butter, Aloe Vera and Shea Butter. All those have been used to allegedly treat or prevent Acne Scars.
Some creams also contain Vitamin E, although many studies have now shown that vitamin E does nothing to a scar. Biological Oils (Rose Hip Oil or Emu Oil), Plant Oils, Cocoa Butter and Shea Butter do improve the lipid content of the skin, enhance water retention, and soften the skin texture for a while. Aloe Vera does have some anti-inflammatory properties and may also decrease the redness of newly formed Acne Scars, but that is about it.
Many companies claim their products are superior for unlike other's they do not contain water. Yes, right, theirs contain mainly Aloe Vera gel which is, naturally, mainly water.
Acne Scars are not caused because your skin is dry. Rather Acne Scars develop far below the skin's surface due to extreme strain, stress, and trauma that eventually breaks down the skin's support structure. No moisturizer in the world can prevent that kind of injury and damage to the skin from taking place.
Topical creams for treatment in combination with chemical peels
Treatments that combine harsh glycolic acid peels and tretinoin or L-ascorbic acid (Vitamin C), or combinations with lactic acid, citric acid or some other such hydroxyl acids have been tested, albeit only on very few subjects: 10 patients in one of the few studies published, according to pubmed.gov http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed)
The study says both tretinoin and L-ascorbic acid when used daily for 12 weeks after glycolic peeling —each and every day— can help with newly formed Acne Scars a little, although it may have adverse side effects such as redness and scaling.
Now, tretinoin is not for women who are pregnant or about to get pregnant for it may cause damage to the growing child in mom’s belly, and is also contraindicated for mothers that breastfeed their baby.
What are these studies findings? “Elastin content within the reticular and papillary dermis can increase with topical 20% glycolic acid combined with 0.05% tretinoin emollient cream therapy; increased epidermal thickness and decreased papillary dermal thickness is found in treated Acne Scars when compared with untreated Acne Scars; combined epidermal and papillary dermal thickness in Acne Scars treated with topical regiments approaches that of normal skin.”
All right! The epidermis gets thicker with those after the fact professional procedures: 20% glycolic peels every single day (applied by a skilled nurse) followed by the topical application of a skin regenerating ingredient: tretinoin or ascorbic acid. Now, what do they do to existing scars —those showing up as Acne Scars? Well, since the dermis gets thicker their appearance diminishes a little.
Read that again: what may diminish a little is their appearance, according to the subjects treated and the “researchers involved”, not the scar tissues within.
Let’s face it. In terms of treatment to existing tears to the dermis those methods do nothing. In terms of prevention they do not possibly do enough of what is absolutely necessary. The very best they can do, if and only if the ingredients are in enough concentration in the products and if they are applied with discipline at least two to three times a day, is to improve the skin barrier’s lipid content and seal in water for a few hours after application. They may also thicken and/or plump up the epidermis making it a little softer and may make the stripe lines that remain in the dermis less visible for a short while.
So, to be very honest, when you use these products to treat Acne Scars, improvement, if any, is almost imperceptible. Some find a little improvement, especially in early Acne Scars, whereas for most people they make no difference.
Why do acne scar creams have such a low rate of effectiveness?
The explanation may very well emerge from understanding that the skin matrix is responsible for the skin's mechanical properties, including firmness, strength, suppleness, and elasticity. Acne Scars are tears in a skin matrix affected by atrophy, a condition characterized by exactly the contrary of those just mentioned. Yes, skin affected by Acne Scars is characterized by weakness, thinning, roughness, sagging, stiffness, and decrease in the size of tissues, diminished cellular proliferation, and decreased function, also called atrophia.
The skin matrix is a precious resource which is both produced and consumed quite frequently during our lives. On one hand, skin matrix is continuously synthesized by fibroblasts. On the other hand, whenever it is damaged, malformed or worn out, skin matrix -particularly the structural proteins collagen and elastin- is broken down into fragments by collagenase and gelatinase enzymes, also called matrix metalloproteinases (MMP) and then recycled. By digesting or chopping up key matrix proteins, such as collagen and elastin, MMP enzymes play an underappreciated yet critical role in skin physiology.
In healthy, youthful skin, the synthesis and degradation of the matrix are in balance: damaged or redundant matrix is degraded while the deficit is replenished by the ongoing synthesis. Unfortunately, this intricate balance gets disrupted because of hormonal imbalances, mal nutrition, or as we age, too little of the matrix is synthesized and too much is degraded. As with any supply-demand imbalance, it can be improved by either increasing supply (boosting synthesis of the matrix) or reducing demand (inhibiting the breakdown).
In particular, the synthesis of elastin is physiologically important, for although elastin is only 2% of the total protein in the dermis, those skin fibers provide the resiliency of skin. Elastin synthesis and the regulation of the quantity of cross-linked insoluble elastin and collagen fibers depend on the interaction between three factors. The first is the presence of active fibroblasts, which secrete the soluble precursor of elastin, tropoelastin. The second is the relative amount of several skin matrix components within the skin also secreted by fibroblasts. The third are enzymes that are responsible for both the cell degradation processes that allow for the breakdown of dead cells into their component amino-acids and their re-use for the creation of new proteins (amino-acid chains).
So beware of creams that contain soluble collagen and/or elastin for they will NOT do the trick. What is needed is the biosynthesis and proper self-assembly of complex skin structures from within your body. The first step in elastic fiber formation is the appearance of small cell surface-associated elastin globules (soluble tropoelastin) that increase in size with time (microassembly). The elastin globules are eventually transferred to pre-existing elastic fibers in the extracellular matrix where, through an intricate and orchestrated biological process, they coalesce into larger structures (macroassembly) and become crosslinked funtional fiber-like polymers with reversible deformation and high resilience.
Collagen and elastin synthesis boosters may fail or fall short in people affected by atrophic skin.
The newest acne scar treatments and prevention products are aimed at replenishing skin matrix by stimulating the synthesis of collagen or elastin (e.g. ascorbic acid, copper peptides, palmitoyl pentapeptide, oligopeptides and other). Unfortunately, this approach fails or falls short in most people affected by atrophic skin, presumably due to the particular chemistry of skin affected by such condition and an inability to respond to matrix synthesis boosters.
Their failure to treat existing Acne Scars is most probably due to something crucial missing in those products; an element that would help your body to get rid of scar tissues. In fact, your body needs two things to accomplish this.
One, your body needs to be able to differentiate or identify scar tissue from the surrounding functional tissues in the skin matrix. Second, it must be able to degrade the proteins that those scar tissues are made off and separate their component amino-acids to then eventually use them to create new skin matrix elements.
This can only be achieved by the action of two types of ingredients that act in concert. One is messenger molecules that are able to bridge communication between cells and allows them to differentiate scar tissues from functional healthy tissues and trigger fibroblast proliferation. The other crucial ingredient is enzymes that dissolve the non functional, worn out, or damaged tissues that were identified by the messenger molecules.
Combined methods that include some form of abrading —to physically break down some of the more superficial scarring—, and a topical product that contains not just moisturizing enhancers or collagen synthesis boosters, but also cell communicating ingredients and enzymes that ‘dissolve’ damaged cells and scar proteins that can yield significant improvements.
Such product can also effectively prevent Acne Scars.
What needs to be in products to prevent Acne Scars?
One may think that boosting collagen formation from within would be a promising approach for preventing Acne Scars, as it would strengthen the skin matrix and skin with enhanced strength which is the opposite of atrophic skin susceptible to tearing when over-stretched.
Palmitoyl pentapeptide —the basis of StriVectin-SD, a cream that with aggressive marketing as a youth-restoring alternative to Botox has become a big seller in the past years— seems to be the prominent ingredient of this new approach by the cosmetic industry in its quest to profit from consumer’s burning desires to have flawless skin.
Chemically speaking, palmitoyl pentapeptide-3 consists of five amino acids linked together and attached to a fatty acid to enhance oil solubility for the sake of better skin penetration. It is structurally related to the precursor of collagen type I (a.k.a. procollagen type I). Researchers found that when added to the culture of fibroblasts (the key skin cells); palmitoyl pentapeptide-3 stimulated the synthesis of the key constituents of the skin matrix: collagen, elastin and glycosaminoglycans. How exactly palmitoyl pentapeptide-3 did that remains unclear, although a number of theories exist.
Unfortunately, the ability to improve the productivity of skin cells in the test tube does not always translate into an effective skin treatment. Few promising test tube discoveries ever become an established therapy. Clinical studies of palmitoyl pentapeptide-3 do exist but all of them (to our knowledge) have been conducted or sponsored by the manufacturers (Sedema and Proctor & Gamble). This does not necessarily make the studies biased, but potential conflict of interests is always a red flag. Unfortunately, this situation is typical. Early studies of patented chemicals are almost always sponsored by manufacturers. It usually takes a long time before completely independent research is conducted.
So far testing has been done on only a few subjects and thus the clinical data is still too skimpy to view palmitoyl pentapeptide-3 as a proven stretch-mark treatment or preventative measure at this time. The molecule is an artificial man made chemical synthesized in a laboratory. It is reported to be safe but it has not gone through the extensive clinical trials necessary for it to be approved as a drug.
The manufacturers don’t seem to be seeking such approval as they prefer to market acne scar treatments as cosmetic products —designed to change the appearance of skin and not its structure— which are not subject to the same approval by the FDA as drugs are.
In fact, they do not seem to be all that interested in the results of the pentapeptide chemical for Acne Scars since they are using it as the grounds of a good story on how it happens to also be good for wrinkles, which is much larger market. They use high-tech claims to attract customers by highlighting the "science" and "technologies" behind their product.
Since the cosmetic industry is largely left to monitor itself and the Food & Drug Administration gets involved only when products have adverse reactions or change the structure of the body, the companies prefer to say they change the appearance of Acne Scars or wrinkles instead of saying they diminish them which is a structural change. You and me continue to be hoodwinked by the cosmetics industry's ingenious marketing and are left to our own devices to monitor such claims.
Although the Federal Trade Commission (FTC) monitors advertising for unfair or deceptive claims, it isn't too aggressive on the cosmetics industry. "Our priority is to ensure that if a product is claiming a health benefit that there are enough trials to back that. If there are general appearance-enhancement claims, those are not high in our prosecution list," says Heather Hippsley, assistant director for the FTC's advertising-practices division in an interview published in Newsweek in November 2004.
Risks of man made synthetic chemicals
The problem with man made chemicals or isolates is not only that they may or may not be effective and require extensive and expensive clinical trials but also that they run the risks of having harmful effects in the long run. We have seen many products rushed to market on the back of inadequate studies and later withdrawn after years of use that may have affected some people’s lives adversely. We do not live in a perfect world and what scientists may consider as safe chemicals one day could well be banned the next day on the basis of new research.
Now, again: EVEN IF THE CHEMICALS ARE PROVEN TO BE SAFE, boosting collagen formation may not be enough to prevent Acne Scars. It is also necessary to degrade the existing damaged and worn out cells. And not only to get rid of them and their ugly marks on our body, but also the release of their components makes amino acids available or building blocks our system needs to create new collagen, elastin, and skin matrix cells.
Scar Less Healing
"An abscess and its subsequent scar is not an evolutionarily optimized end point for today's injuries," Dr. Mark Ferguson, D.D.S., Ph.D., professor in the faculty of life sciences at the University of Manchester, England, says. The abscess and scarring response, with its massive inflammatory overdrive, is optimized for a very different type of skin lesion than those occurring nowadays where hygiene and clean bodies is the rule. The abscess and scar is induced by this inappropriate inflammatory response.
Surgery lesions, lesions to the cells lining the sebum ducts (which causes acne) and also lesions that emerge from overstretching the skin should therefore be ideal candidates for healing, without complications, by a regenerative wound healing mechanism rather than a scarring mechanism. And the outcome should be characterized by scar less healing.
The healing process should be very much like what our system accomplishes for fetal wounds which heal quickly by regenerating cells and leaving no trace behind, whatsoever. For the whole system there is signaling the growing baby that it is being taken care of properly.
This is what is missing in all the products out there. Something that would signal your body it is being taken care of properly, and does not need to react with its inflammatory army.
A Surprising Solution by Life's Genius
Fortunately there is a complete & balanced solution for acne scar prevention and treatment. One packed with antioxidants, collagen, elastin boosters, enzymes, and cell communicating ingredients that contribute to orchestrate the intricate balance between the degradation of cells that are dying periodically and/or cells that have become damaged by overstretching and the use of their constitutive amino-acids for the reproduction of new cells and all the necessary structural elements of healthy skin.
It is not a chemical ,man made drug, clever concoction of isolates, pharmaceuticals, herbs, moisturizing botanical oils, or extracts designed in a laboratory or cosmetic industry. No. It is a natural compound of biological active molecules that is already the most complete and balanced solution created by a living creature to protect and fully repair its skin when damaged. And although this creature is in an evolutionary stage different than humans, nevertheless its skin is made of the same structural elements we find in human skin: collagen, elastin and glycosaminoglycans.
Glycosaminoglycans are the water holding molecules in the dermis responsible for providing binding, hydration, and swelling pressure to tissues enabling them to withstand compression and stretching forces which thus prevent tearing and scarring of the deep layers of the skin.
The acne scar prevention and treatment cream made with this natural, biological solution is natural, not some isolate derived or extracted from it. It is not only effective for preventing Acne Scars but is also safe since it is totally compatible with living cells.
The product comes in two versions. One plain to prevent Acne Scars which is best used to treat newly formed Acne Scars. The second is a home microdermabrasion version with is embedded with micro-crystals to abrade Acne Scars that are older or rough on the surface as they help to break down or exfoliate damaged skin physically —while massaging the crystals—, and thereby facilitate the penetration of the cream deeper within the skin.
It Works As A Different Defense System
It works because it operates at a different level than our human immune or defense system when it is subject to stress and damage inflicted to the dermis by such events as overstretching of skin fibers to the point of breaking.
It is geared as a different evolutionary immune response and cell regeneration system by a family of invertebrates (spineless animals). It is known as the innate immune system; also present as a first line of defense and immediate response against infections and foreign matters in our human body, complementing our adaptive immune system.
The innate immune system is comprised of the cells and mechanisms that defend the host from infection by other organisms or from foreign materials in a non-specific manner. This means that the cells of the innate system recognize, and respond to, pathogens in a generic way, but unlike the adaptive immune system, it does not confer long-lasting or protective immunity to the host.
Although apparently less sophisticated than the immune systems of vertebrates, invertebrate immunity is much older in terms of its evolution. This likely served as the progenitor to sophisticated vertebrate systems and also has apparently served these animals well enough to keep their lineage alive for the past several hundred million years.
Invertebrates respond to injury and insult by regenerating damaged cells, and even full organs and their skin, without an immoderate inflammatory reaction and yield quick results and scar less healing! Yes, this is accomplished by little creatures that us, arrogant humans, many times consider an inferior form of life in a less evolved stage.
Unlike clever herbal, botanical, chemical or cosmeceutical concoctions designed in a pharmacy, or by the cosmetic industry, a complex natural substance secreted by snails has been proven to be a complete and balanced solution for scar less healing of skin lesions —and its effects on Acne Scars and scars far exceed attempts to mimic life's genius in the laboratory.
Auto-Immune Moderator
Discouraging Over-Zealous Immune System Responses that Attack Healthy TissueThe molecules in the biological substance signal the body that it is being taken care of and need NOT respond to disturbing agents with uncontrolled inflammatory reactions, for it is being supplied with the proper proteins, enzymes and nutrients necessary to quickly control bacteria and to trigger scar less healing. Thus in a totally different way than our evolutionary drive has conditioned us humans to over-respond to those factors, from within, as the most effective means to thrive in an environment that was dominated by infectious bacteria.
For such was homo sapiens reality during millions of years and until society learned hygiene and modern science discovered antibiotics —which by the way have an anti-inflammatory effect that is now deemed to be a far more important effect for people who suffer severe acne and rosacea than it is the anti-biotic effect (which means anti-life) that kills bacteria.
Topical application of the substance created by this little creature, soon after the first signs of lesions prevents the cells from initiating the signaling cascade that leads to inflammatory reactions and healing through the scarring pathway. It accomplishes so by altering the local environment in a way that favors a scarless healing pathway.
Treatment with BIO acne scar CREAM operates through a removal process called hydrolysation. By continued application on damaged tissues messenger molecules recognize damaged proteins and act in concert with enzymes that gently strip the skin to remove the build-up of scar tissues. These enzymes go to work like biological catalysts on each individual cell. They clean out the debris, open clogged pores, consume the dead material, open up the vascular system to bring new oxygen into the cells. And trigger and speed proliferation of fibroblasts and all the structural components of healthy skin including the water holding molecules, collagen and elastin skin fibers which finally get assembled in an orderly or orchestarted way, thus minimizing scars and marks.
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Skin is not in tight layers like everybody thinks". "We're not just onions, you can't just rip off a layer and voila - there's everything new. If you viewed a section of skin under a microscope it would look like a series of hills and valleys." says Dr. Danne Montague-King, the man who zapped Brad Pitt's scars and made Gwyneth Paltrow even prettier. And when refering to the action of enzymes on skin he adds: "The remaining cells are 'fed' or 'rebuilt' using the amino acids that are released from the metabolic digestion of the damaged and dead cells. This rejuvenates the skin too, for it's rather like charging a battery. The end result is like making the 'cleansers' of the cells strong again. If they're strong they'll dissolve things that aren't supposed to be there like abnormal scar tissues, pore plugs, excess and hardened sebum, injured and worn out cells, pollutants and free radicals. If they're weak they won't. |
The biological substance operates for its creator in such an irreducible complex way that it can be a challenge to try to explain how specifically it modulates the response of the the immune cells, especially of the macrophages, which are the oldest and most consistently preserved immunologic competent cells known. When these cells are activated, they stimulate a cascade of events which enhances immunity and skin repair. All the functions, including phagocytosis (ability to engulf foreign cells, materials and particles), release of certain cytokines (intercellular "messages") and the processing of antigens are improved.
We have now described the problem, which is already the first part of the solution:
The immoderate inflammatory response of our body when hormonal imbalances weaken the skin or deplete it of the collagen synthesis boosters, the cell communicating ingredients and the enzymes, that need to act in concert to strengthen and repair your skin.
They are the molecules that protect the skin from overstretching and are capable of ‘dissolving’ damaged cells and scar proteins, trigger collagen and new elastin formation, and make the skin's structure strong by replenishing glycosaminoglycans, the water holding molecules in the dermis responsible for providing binding, hydrating and swelling pressure to tissues, enabling them to withstand compression and stretching forces and thus prevent tearing and scarring of the deep layers of the skin.
Now you may stop procrastinating and go get the second half of the solution with confidence.
Order BIO SKIN CARE CREAM now! And strengthen your skin to avoid having to use the product to get rid of scars and Acne Scars when it may be too late for optimal results!
BIO ACNE CARE 
Gentle but effective acne treatment serum for pimples & acne cysts
The product is oil free and contains the following ingredients that act in concert to yield benefits that go beyond the sum of those of their specific parts:
a) our biological Helix Aspersa Müller Glycoconjugates with antioxidant, antimicrobial & skin regeneration properties to heal skin lesions within the follicles, control acne bacteria and prevent and get rid of acne scars;
b) the active extract of the bark of the Black willow ( Salix Nigra) tree to enhance cell renewal on the surface of the skin, unclog pores and reduce acneic skin flora (Propionibacterium acnes and Staphylococcus aureus). The actual content of willow (Salix Nigra) extract expressed as standarized salicylic acid is less than 0.5%. The Salix Nigra extract also provides natural B-hydroxy acid activity, without the skin irritation commonly associated with synthetic salicylic acid;
c) modified glucomannan (carbohydrate) -high molecular weight heterpolysaccharides made up of glucose and mannose derived from the Japanese Konjac tuber (root)- that reduce the surface tension of oil and facilitates its dispersion into droplets. These droplets get distributed evenly along the skin’s surface, minimizing their presence and oily feel;
d) Hyaluronic Acid a glycosaminoglycan (also present in the snail serum) to deeply moisturize the skin and restore the capacity of the skin to hold in moisture; and seaweed extracts that provide moisture and trace minerals necessary for the recovery of damaged skin cells; and sodium salt of pyroglutamic acid (naturally in human skin) moisturizer;
e) Japanese Licochalcone LR-15 from Licorice (Glycyrrhiza inflate) extract which clinicals (*) in Japan have shown that at very low concentration reduces undesired p. acnes and other acneic skin flora, is anti-irritating, anti-inflammatory and reduces sebum output.
Apply a thin layer twice a day on all the area affected with acne (whole face, chest or back) and then always use sun protection. If you are allergic to salycilic acid or to aspirin do not use the product and if you experience stinging or irritation (very unlikely) you must stop using the product and consult your physician.
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Made in the USA. One Month Supply 50 grams = 1.76 oz
50 Grams in Airless Pump Bottle.
Regular Price: $54.98
For a limited time: $49.95
(*) A New Dermatological Availability of the Flavonoid Fraction from Licorice Roots-Effect on Acne
Journal of Society Cosmetic Chemists Japan, VOL.37; NO.3; PAGE. 179-186(2003) Authors: Kambara Toshimitsua, Zhou Y, Kawashima Yoshihitoa, Kishida Naokoa, Mizutani Kenjia, Ikeda Takaoa, Kameyama Koichirob.
a Research Center, Maruzen Pharmaceuticals Co., Ltd., 1089-8 Sagata, Shin-ichi, Fukuyama, 729-3102 Hiroshima, Japan. bAoyama Dermatological Clinic, dr@aoyamahihuka.com 5-1-3 Aoyama 8F Minato-ku Tokyo 107 Japan.
Abstract: Licochalcone-A, Polyol Soluble Licorice Extract P-U (now in the market as Licochalcone LR-15), prepared from the roots of Glycyrrhiza Inflata Batalin shows several activities such as inhibitory actions of testosterone 5 ALPHA-reductase, lipase and phospholipase A2, as well as androgen receptor antagonist, antimicrobial and SOD-like antioxidant actions, which relate to skin care, especially the suppression of acne formation and development. On basis of this evidence, a trial with acne patients was carried out and the efficacy of the extract was demonstrated clinically.
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The Biological Skin Treatment Complex
The biological activity in human skin of a complex carbohydrate and protein compound, collected from a live creature that produces it to regenerate its skin and organs when damaged, enhances the flow of information that is necessary to repair skin damage in an orderly, orchestrated way, with scarless healing.
The serum in our BIOCUTIS products has the unique ability to dissolve damaged and abnormal collagen protein fibers in the dermis where they were created to repair damaged tissues that may result when inflammatory reactions destroy our own tissues in their quest to protect us from invading bacteria or foreign materials. It does so through the action of "digestive" enzymes that breakdown proteins into their amino acid components in coordination with the glycomolecules in the compound that help to discern damaged cells from normal functional cells.
When the liquid active biological ingredient is combined with lipids (Olive Oil derivatives) to make it into a cream and micro-crystals are added to the final product, it accomplishes results for old and rough acne scars through a polishing or microdermabrasion action, while also hydrating deeply, strengthening cell membranes and triggering an orderly regeneration of the skin matrix.
We collect the rich biological ingredient by using a humanely method without harming any of the little creatures.
BIO ACNE CARE ™ 
A serum for moderate acne breakouts and for cystic acne. Contains the following ingredients acting in concert to yield benefits that go beyond the sum of those of the components:
a) Helix Aspersa Müller Glycoconjugates with antioxidant, antimicrobial & skin regeneration properties to heal skin lesions within the follicles, control acne bacteria and prevent and get rid of acne scars;
b) The active extract of the bark of the Black willow ( Salix Nigra) tree to enhance cell renewal on the surface of the skin, unclog pores and reduce acneic skin flora (Propionibacterium acnes and Staphylococcus aureus). The actual content of willow (Salix Nigra) extract expressed as standarized salicylic acid is less than 0.5%. The Salix Nigra extract also provides natural B-hydroxy acid activity, without the skin irritation commonly associated with synthetic salicylic acid;
c) Modified glucomannan (carbohydrate) -high molecular weight heterpolysaccharides made up of glucose and mannose derived from the Japanese Konjac tuber (root)- that reduce the surface tension of oil and facilitates its dispersion into droplets. These droplets get distributed evenly along the skin’s surface, minimizing their presence and oily feel;
d) Hyaluronic Acid a glycosaminoglycan (also present in the snail serum) to deeply moisturize the skin and restore the capacity of the skin to hold in moisture; and seaweed extracts that provide moisture and trace minerals necessary for the recovery of damaged skin cells; and sodium salt of pyroglutamic acid (naturally in human skin) moisturizer;
e) Licochalcone LR-15 from Licorice (Glycyrrhiza inflate) extract which clinicals in Japan have shown that at very low concentration reduces undesired p. acnes and other acneic skin flora, is anti-irritating, anti-inflammatory and reduces sebum output.
50 Grams in Airless Pump Bottle.
Regular Price: $54.98
For a limited time: $49.95
BIOSKINCLEAR ™ 
An oil free moisturizer gel for acne, rosacea and facial scars. Heals lesions to the cells lining the hair follicles which is the root cause of inflammatory acne. Removes dead cells, unclogs sebum canals and dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the proliferation of antimicrobials that control acne bacteria. Boosts reproduction of glycosaminoglycans, the molecules that retain water, thus truly moisturizing the skin from within. Tells the body it is being taken care off and can moderate an otherwise extreme inflammatory reaction that may end up destroying healthy skin cells and creating crater like scarring and not only the acne bacteria.
50 gram (1.76 oz) airless pump bottle $49
25% off for two or more.
BIOSKINEXFOL™
A home microdermabrasion cream with micro-crystals that breakdown hard, rough and old scar tissues, and allow for a deeper penetration of the natural skin regeneration complex that is in the cream.
BIOSKINCARE ™ 
A natural skin care cream (without the micro-crystals) that triggers the regeneration of damaged cells and replenishes the lipid barrier of the skin while preventing and removing scars after healing of burns, injuries, wounds or surgery; Acne Scars; aberrant hypertrophic and keloid scars; keratois pilaris, actinic keratosis scales, dermatitis, dryness, cracked skin and all types of skin blemishes.
50 gram jar = $59.98
Two or more 20% discount
BIO SKIN REJUVENATION ™
Same cream base and enzymes as in BIOSKINCARE to "digest" or dissolve blemishes, speed skin turnover and tighten skin, and two added ingredients: one is a human growth factor peptide, derived from the melanocyte-stimulating-hormone. Blocks melanin synthesis, and reduces the formation of unwanted pigmentation, allowing control over skin tone and brown spots. The other is a natural plant extract that takes away dark pigmentation. Leaves skin bright and refreshed!


